Validation of high-performance liquid chromatography-boron-doped diamond detection for assessing hepatic glutathione redox status.

Determination of Clinically Relevant Compounds using HPLC and Electrochemical Detection with a Boron-Doped Diamond Electrode

Electrochemical detection of sugar-related compounds using boron-doped diamond electrodes.

Electrochemical detection of sugar-related compounds was conducted using a boron-doped diamond (BDD) electrode as a detector for flow-injection analysis (FIA). Sugar-related compounds oxidize at high applied potentials, for which the BDD electrode is suitable for electrochemical measurements. Conditions for an FIA system with a BDD detector were optimized, and the following detection limits wer...

Electrochemical oxidation of chlorophenols at a boron-doped diamond electrode and their determination by high-performance liquid chromatography with amperometric detection.

Anodically pretreated diamond electrodes have been used for the detection of chlorophenols (CPs) in environmental water samples after high-performance liquid chromatographic (HPLC) separation. The anodization of as-deposited boron-doped polycrystalline diamond thin-film electrodes has enabled the stable determination of phenols over a wide concentration range. Prior to the HPLC analysis, a comp...

Simultaneous Detection of Monoamine and Purine Molecules using HPLC with a Boron-Doped Diamond Electrode

Most biochemical analyses typically examine molecules from the same neurochemical family, like dopamine and serotonin (monoamines), and GABA and glutamate (amino acids). In this present study, two different families, monoamines and purines, are being investigated using high-performance liquid chromatography (HPLC) with a boron-doped diamond (BDD) electrode. There is considerable data demonstrat...

Simultaneous detection of purine and pyrimidine at highly boron-doped diamond electrodes by using liquid chromatography.

Highly boron-doped diamond (BDD) electrode, have been examined for simultaneous detection of purine and pyrimidine bases in mild acidic media by using HPLC with amperometric detection. Cyclic voltammetry at as-deposited (AD) and anodically oxidized (AO) BDD were used to study the electrochemistry and to optimize the condition for HPLC applications. At AO BDD electrode, due to its higher overpot...